Travelers who live/work int the U.S. and have a green card are required to follow the U.S. travel regulations for Cuba.
While we aren't aware of any specific extra stipulations that would make it not possible for green card holders to travel to Cuba (as long as the rules are followed), we recommend they contact an immigration lawyer/expert or someone in the U.S. government with knowledge of travel rules for green card holders to make sure that there is nothing that would cause any issues.
Travelers may be able to get an answer from OFAC (Office of Foreign Assets Control) within the U.S. Treasury Dept., which sets and enforces all the Cuba regulations. We recommend that travelers call the "Toll Free Hotline Number" contact at the bottom of the page below:
Callers should be able to leave a message and OFAC officials will respond within a day or so.
For answers to more questions about travel in Cuba, feel free to send a message to one or several of our local Cuba planners through the link on their profile page. You can message locals for free before booking to ask questions and get a sense of who would be the best fit!